Pep2-AVKI

• Target :

  IGluR

• Related Pathways :

  Neuroscience|||Membrane transporter/Ion channel

• Bioactivity :

  Pep2-AVKI is an inhibitor peptide that selectively disrupts binding of the AMPA receptor subunit GluA2 (at the C-terminal PDZ site) to protein interacting with C kinase (PICK1) . Does not affect binding of GluA2 to GRIP or ABP and does not increase AMPA current amplitude or affect long term depression (LTD) .

• Smiles :

  [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O

• Molecular Formula :

  C60H93N13O17

• Molecular Weight :

  1268.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1315378-69-8