Elabela (19-32)

CAT: 0931-TP1923-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-TP1923-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1886973-05-2

Target

Arrestin, Apelin receptor

Related Pathways

GPCR/G Protein

Bioactivity

Potent apelin (APJ) receptor agonist (Ki = 0.93 nM) . Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.

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C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]1CCC(=O)N1)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CS)=O)CCSC)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(=O)N5[C@H](C(O)=O)CCC5)CC6=CC=CC=C6)=O)CCC4)[C@H](C)C)=O)CCCNC(=N)N)=O)CO)=O)=O)CC(C)C)=O)CCC2

Molecular Formula

C75H119N25O17S2

Molecular Weight

1707.03

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Elabela (19-32)

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