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Morachalcone A

CAT: 0931-TN4580-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4580-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
76472-88-3
Target
Tyrosinase, NO Synthase
Related Pathways
Immunology/Inflammation, Proteases/Proteasome
Purity
0.97
Bioactivity
Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM) ; it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells against glutamate-induced oxidative stress, with EC50 values of 35.5±2.1 uM. It exhibits potent inhibitory activity on nitric oxide production in RAW264.7 LPS-activated mouse macrophage cells with IC50 value of 16.4 microM.
Smiles
C\C(C)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O
Molecular Formula
C20H20O5
Molecular Weight
340.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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