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Morachalcone A

CAT: 0804-HY-N3246-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3246-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Morachalcone A is a naturally-occurring aromatase inhibitor (IC50=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide -induced nitric oxide production[1][2][3].
CAS Number
76472-88-3
UNSPSC
12352005
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/morachalcone-a.html
Solubility
10 mM in DMSO
Smiles
OC(C=C(O)C=C1)=C1/C=C/C(C2=C(C(C/C=C(C)/C)=C(O)C=C2)O)=O
Molecular Formula
C20H20O5
Molecular Weight
340.37
References & Citations
[1]Brandt D R, et al. The synthetic preparation of naturally-occurring aromatase inhibitors, morachalcone A, isogemichalcone B, and isogemichalcone C[J]. Tetrahedron, 2013, 69 (47) : 9994-10002.|[2]Kang Y J, et al. Inhibitory effects of morachalcone A on lipopolysaccharide-induced nitric oxide production in raw 264.7 cells[J]. 2009.|[3]Ferlinahayati, et al. Phenolic constituents from the wood of Morus australis with cytotoxic activity. Z Naturforsch C J Biosci. 2008 Jan-Feb;63 (1-2) :35-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
TN4580-01Morachalcone A

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