Products for Research Use Only
RegisterLogin

2-Methoxystypandrone

CAT: 0931-TN2775Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TN2775Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
85122-21-0
Target
NOS, IκB/IKK, Bcl-2 Family, NF-κB, MMP, JAK, STAT, GSK-3, COX, TNF, Wnt/beta-catenin
Related Pathways
Neuroscience, JAK/STAT signaling, Angiogenesis, Cytoskeletal Signaling, Chromatin/Epigenetic, Immunology/Inflammation, Proteases/Proteasome, Tyrosine Kinase/Adaptors, Apoptosis, Stem Cells, NF-κB, PI3K/Akt/mTOR signaling
Bioactivity
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-ÎoB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity. 2-Methoxystypandrone concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins.2-Methoxystypandrone has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption.
Smiles
COC1=CC(=O)c2c(O)c(C(C)=O)c(C)cc2C1=O
Molecular Formula
C14H12O5
Molecular Weight
260.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
TN9304-012,2,2-Trifluoroacetamide
T377092,2,2-Trichloroethanol
T125691-012-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl bromide
T9894-012-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl methanesulfonate
TN9630-012,2':6',2''-Terpyridine
T5650-012,2':5',2''-Terthiophene
T203822-012,2-Dibromo-2-cyanoacetamide
TYD-02659-012,2'-Azobis[2- (2-imidazolin-2-yl) propane] dihydrochloride
TYD-00800-012,2,2-Trifluoro-N- (2-hydroxyethyl) acetamide
T39961Bcl-2-IN-2

Alternative Products

CatalogName
HY-N17382-Methoxystypandrone
PC1003049-012,2,2-Trifluoroethyl 2,2,2-trichloroacetate
H 038-0012'- , 2''-, 2''', 2'''', 2''''', 2''''''- Hexadeoxy- 2'-, 2'', 2''', 2'''', 2''''', 2''''''- hexafluoro- cyclic hexaadenosine monophosphate (2',2'',2''',2'''',2''''',2''''''-Hexa-F-c-hexadAMP / cFA6), sodium salt
PC32719-012,2,2,2'-Tetrafluoroacetophenone
OR1009873-012,2,2,2-Ethylenedinitrilotetraethanol
290342-012,2,2-Trifluoroethyl 2,5-bis (2,2,2-trifluoroethoxy) benzoate
TRC-T790240-50MG2,2,2-Trifluoroethyl 2-Hydroxy-5-(2,2,2-trifluoroethoxy)benzoate
TRC-T790200-100MG2,2,2-Trifluoroethyl 2,5-Bis(2,2,2-trifluoroethoxy)benzoate
290343-012,2,2-Trifluoroethyl 2-hydroxy-5- (2,2,2-trifluoroethoxy) benzoate
D3554-34-012’,2’-Difluoro-2’-deoxyuridine (2’-Deoxy-2’,2’-difluorouridine)

Popular Products