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Jatrophane 2

CAT: 0931-TN2727Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN2727Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
210108-86-4
Target
Antifection, P-gp
Related Pathways
Microbiology/Virology, Neuroscience, Membrane transporter/Ion channel
Bioactivity
2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6 (17),11E-diene (Jatrophane 2) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera) . Jatrophane 2 also demonstrates the most powerful inhibition of P-gp, higher than R (+) -verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR) .
Smiles
[H][C@]12[C@@H](OC(=O)c3ccccc3)[C@@](C)(C[C@]1(O)[C@@H](OC(C)=O)[C@@H](C)\C=C\C(C)(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=C)[C@@H]2OC(C)=O)OC(C)=O |t:26|
Molecular Formula
C39H50O15
Molecular Weight
758.814
Shipping Conditions
Ice Packs
Storage Temperature
-20°C