Jatrophane 2

• Target:

  Antifection|||P-gp

• Related Pathways:

  Microbiology/Virology|||Neuroscience|||Membrane transporter/Ion channel

• Bioactivity:

  2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6 (17),11E-diene (Jatrophane 2) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera) . Jatrophane 2 also demonstrates the most powerful inhibition of P-gp, higher than R (+) -verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR) .

• Smiles:

  [H][C@]12[C@@H](OC(=O)c3ccccc3)[C@@](C)(C[C@]1(O)[C@@H](OC(C)=O)[C@@H](C)\C=C\C(C)(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=C)[C@@H]2OC(C)=O)OC(C)=O|t:26|

• Molecular Formula:

  C39H50O15

• Molecular Weight:

  758.814

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  210108-86-4