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Jatrophane 5

CAT: 0804-HY-N7305Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N7305Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Jatrophane 5 is a natural product of Jatropha carcas L. Jatrophane 5 has powerful inhibition of P-gp, higher than R (+) -verapamil and Tariquidar (HY-10550) in colorectal multi-drug resistant cells (DLD1-TxR).
CAS Number
210108-89-7
UNSPSC
12352005
Target
P-glycoprotein
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jatrophane-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CN=C1)O[C@H]([C@H](O)[C@H]2OC(C)=O)C(C)(C)/C=C/[C@H](C)[C@H](OC(C)=O)[C@](C[C@@](C)(OC(C)=O)[C@@H]3OC(C4=CC=CC=C4)=O)(O)[C@@]3([H])[C@@H](OC(C)=O)C2=C
Molecular Formula
C41H49NO14
Molecular Weight
779.83
References & Citations
[1]Jadranin M, et al. Jatrophane diterpenoids from the latex of Euphorbia dendroides and their anti-P-glycoprotein activity in human multi-drug resistant cancer cell lines. Phytochemistry. 2013;86:208-217.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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