Physalin B

• Target:

  Autophagy|||NOD|||Apoptosis|||Akt|||NF-?B|||Nrf2|||PI3K

• Related Pathways:

  Autophagy|||Apoptosis|||PI3K/Akt/mTOR signaling|||NF-?B|||Immunology/Inflammation|||Cytoskeletal Signaling

• Purity:

  0.984

• Bioactivity:

  Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B ameliorates lipopolysaccharide-induced inflammatory response due to acute lung injury by inhibiting NF-?B and NLRP3 through activation of the PI3K/Akt pathway.Physalin B inhibits PDGF-BB-induced VSMC proliferation and migration and phenotypic transformation through activation of the Nrf2 pathway. Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation through activation of the Nrf2 pathway.Physalin B exerts antitumor activity by inhibiting LAP2?-HDAC1-mediated deacetylation of glioma-associated oncogene 1 and hepatic stellate cell activation.

• Smiles:

  [H][C@@]12C (=O) [C@]34O[C@]11[C@@] (C) (OC (=O) [C@@]1 (O) CC[C@@]1 ([H]) [C@@]3 ([H]) CC=C3CC=CC (=O) [C@]13C) [C@H]1C[C@]2 (C) [C@@] ([H]) (CO4) C (=O) O1

• Molecular Formula:

  C28H30O9

• Molecular Weight:

  510.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  23133-56-4