Physalin B

• Target :

  Autophagy|||NOD|||Apoptosis|||Akt|||NF-?B|||Nrf2|||PI3K

• Related Pathways :

  Autophagy|||Apoptosis|||PI3K/Akt/mTOR signaling|||NF-?B|||Immunology/Inflammation|||Cytoskeletal Signaling

• Purity :

  0.984

• Bioactivity :

  Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B ameliorates lipopolysaccharide-induced inflammatory response due to acute lung injury by inhibiting NF-?B and NLRP3 through activation of the PI3K/Akt pathway.Physalin B inhibits PDGF-BB-induced VSMC proliferation and migration and phenotypic transformation through activation of the Nrf2 pathway. Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation through activation of the Nrf2 pathway.Physalin B exerts antitumor activity by inhibiting LAP2?-HDAC1-mediated deacetylation of glioma-associated oncogene 1 and hepatic stellate cell activation.

• Smiles :

  [H][C@@]12C(=O)[C@]34O[C@]11[C@@](C)(OC(=O)[C@@]1(O)CC[C@@]1([H])[C@@]3([H])CC=C3CC=CC(=O)[C@]13C)[C@H]1C[C@]2(C)[C@@]([H])(CO4)C(=O)O1

• Molecular Formula :

  C28H30O9

• Molecular Weight :

  510.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  23133-56-4