Physalin A

• Target:

  JAK|||Autophagy|||STAT|||mTOR|||Apoptosis|||p38 MAPK|||Akt|||NF-?B|||PI3K

• Related Pathways:

  NF-?B|||Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic|||Stem Cells|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Apoptosis|||JAK/STAT signaling

• Purity:

  0.9971

• Bioactivity:

  Physalin A is an anti-inflammatory compound isolated from P. alkekengi with anti-fibrotic effects, regulating the Nrf2 pathway through ERK and p38 to induce detoxification enzymes. Physalin A blocks the activation of the NF-kappaB signaling pathway. Physalin A reduces mammosphere formation by reducing the expression of the GLI1 gene and the YAP1 gene.

• Smiles:

  C[C@@]12[C@]34[C@] ([C@]5 (C) C[C@]1 (OC (=O) C5=C) [H]) (C (=O) [C@] (O) (O3) [C@]6 ([C@] (CC[C@]4 (O) C (=O) O2) ([C@]7 (C) C (=C[C@H]6O) CC=CC7=O) [H]) [H]) [H]

• Molecular Formula:

  C28H30O10

• Molecular Weight:

  526.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  23027-91-0