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Norathyriol

CAT: 0931-TN1990-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1990-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3542-72-1
Target
AMPK, Glucosidase, Akt, DNA/RNA Synthesis, glycosidase, PPAR
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Metabolism, Cytoskeletal Signaling
Purity
0.9955
Bioactivity
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
Smiles
Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O
Molecular Formula
C13H8O6
Molecular Weight
260.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Norathyriol

Norathyriol is a member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C. It has a role as an antineoplastic agent, an EC 2.7.11.13 (protein kinase C) inhibitor and a plant metabolite. It is a polyphenol and a member of xanthones.

CAS Number3542-72-1
PubChem CID5281656
IUPAC Name1,3,6,7-tetrahydroxyxanthen-9-one
Molecular FormulaC13H8O6
Molecular Weight260.20
XLogP2.1
Topological Polar Surface Area107
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count0
Heavy Atom Count19
Formal Charge0
Complexity372
SMILES
C1=C(C=C2C(=C1O)C(=O)C3=CC(=C(C=C3O2)O)O)O
InChI
InChI=1S/C13H8O6/c14-5-1-9(17)12-11(2-5)19-10-4-8(16)7(15)3-6(10)13(12)18/h1-4,14-17H
InChIKey
ZHTQCPCDXKMMLU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Norathyriol
CAS: 3542-72-1
CID: 5281656
Formula: C13H8O6
MW: 260.20
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight260.20
XLogP32.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count0
Exact Mass260.03208797
Monoisotopic Mass260.03208797
Topological Polar Surface Area107 Ų
Heavy Atom Count19
Formal Charge0
Complexity372
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
DAA54272-01Norathyriol

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