Isopropyl ferulate

• Target:

  AMPK|||mTOR|||EGFR|||Akt|||IL Receptor

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||Immunology/Inflammation|||Angiogenesis|||JAK/STAT signaling

• Purity:

  0.9991

• Bioactivity:

  Isopropyl ferulate is a bioactive compound from Rhizoma et Radix Notopterygii (Qianghuo) that exerts strong cytotoxic effects against PANC-1 human pancreatic cancer cells with a PC50 of 17.5 ?g/mL, mechanistic analysis of Isopropyl ferulate via network pharmacology implicates Isopropyl ferulate regulate PI3K/Akt/mTOR, ErbB, and IL-17 pathways. Further validated in IMQ-induced and LPS-stimulated model systems, confirmed its significant modulation of PI3K/Akt/mTOR signaling, supporting the relevance of Isopropyl ferulate in cancer therapeutics.

• Smiles:

  O=C(OC(C)C)C=CC1=CC=C(O)C(OC)=C1

• Molecular Formula:

  C13H16O4

• Molecular Weight:

  236.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  59831-94-6