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Isopropyl ferulate

CAT: 0931-TN1789-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1789-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
59831-94-6
Target
AMPK, mTOR, EGFR, Akt, IL Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Immunology/Inflammation, Angiogenesis, JAK/STAT signaling
Purity
0.9991
Bioactivity
Isopropyl ferulate is a bioactive compound from Rhizoma et Radix Notopterygii (Qianghuo) that exerts strong cytotoxic effects against PANC-1 human pancreatic cancer cells with a PC50 of 17.5 μg/mL, mechanistic analysis of Isopropyl ferulate via network pharmacology implicates Isopropyl ferulate regulate PI3K/Akt/mTOR, ErbB, and IL-17 pathways. Further validated in IMQ-induced and LPS-stimulated model systems, confirmed its significant modulation of PI3K/Akt/mTOR signaling, supporting the relevance of Isopropyl ferulate in cancer therapeutics.
Smiles
O=C(OC(C)C)C=CC1=CC=C(O)C(OC)=C1
Molecular Formula
C13H16O4
Molecular Weight
236.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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