(E/Z) -GO289

• Target:

  Casein Kinase

• Related Pathways:

  Stem Cells|||Metabolism

• Purity:

  0.9968

• Bioactivity:

  (E/Z) -GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z) -GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z) -GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.

• Smiles:

  COc1cc(\C=N 2c(SC)nnc2-c2ccccc2)c(Br)cc1O

• Molecular Formula:

  C17H15BrN4O2S

• Molecular Weight:

  419.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  694522-87-7