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(E/Z) -GO289

CAT: 0931-T9356-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T9356-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
694522-87-7
Target
Casein Kinase
Related Pathways
Stem Cells, Metabolism
Purity
0.9968
Bioactivity
(E/Z) -GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z) -GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z) -GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.
Smiles
COc1cc(\C=N\n2c(SC)nnc2-c2ccccc2)c(Br)cc1O
Molecular Formula
C17H15BrN4O2S
Molecular Weight
419.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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