NRX-252262

• Target:

  Molecular Glues|||E1/E2/E3 Enzyme|||Wnt/beta-catenin

• Related Pathways:

  Cytoskeletal Signaling|||PROTAC|||Stem Cells|||Ubiquitination

• Purity:

  0.9987

• Bioactivity:

  NRX-252262 is a potent enhancer of the interaction between ?-Catenin and its cognate E3 ligase, SCF?-TrCP, inducing mutant ?-Catenin degradation (EC50: 3.8 nM) .

• Smiles:

  COc1cc2CN(Cc2cc1OC)C(=O)c1c(Sc2c(Cl)cccc2Cl)cc([nH]c1=O)C(F)(F)F

• Molecular Formula:

  C23H17Cl2F3N2O4S

• Molecular Weight:

  545.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2438637-61-5