Necrostatin-34

• Target:

  RIP kinase

• Related Pathways:

  Apoptosis|||NF-?B

• Purity:

  0.988

• Bioactivity:

  Necrostatin-34 (2-{[3-cyano-4- (4-methylphenyl) -6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.

• Smiles:

  Cc1ccc(cc1)C1CC(=O)NC(SCC(=O)Nc2nccs2)=C1C#N

• Molecular Formula:

  C18H16N4O2S2

• Molecular Weight:

  384.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  375835-43-1