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Necrostatin-34

CAT: 0931-T9095-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9095-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
375835-43-1
Target
RIP kinase
Related Pathways
Apoptosis, NF-κB
Purity
0.988
Bioactivity
Necrostatin-34 (2-{[3-cyano-4- (4-methylphenyl) -6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
Smiles
Cc1ccc(cc1)C1CC(=O)NC(SCC(=O)Nc2nccs2)=C1C#N
Molecular Formula
C18H16N4O2S2
Molecular Weight
384.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C