Necrostatin-5

• CAS Number :

  337349-54-9

• Target :

  Necroptosis|||RIP kinase

• Related Pathways :

  Apoptosis|||NF-?B

• Purity :

  0.994

• Bioactivity :

  Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-?, with an EC50 of 240 nM.

• Smiles :

  O=C1C=2C3=C(SC2N=C(SCC#N)N1C4=CC=C(OC)C=C4)CCCC3

• Molecular Formula :

  C19H17N3O2S2

• Molecular Weight :

  383.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C