AQX-016A

• Target :

  Others|||PI3K|||Phosphatase|||TNF

• Related Pathways :

  PI3K/Akt/mTOR signaling|||Others|||Apoptosis|||Metabolism

• Bioactivity :

  AQX-016A is an orally active and potent SHIP1 agonist. It is a structural analog of pelorol and is three times more potent than the marine natural product pelorol at the same molar concentration. AQX-016A can activate recombinant SHIP1 enzyme in vitro and stimulate SHIP1 activity. It also inhibits the PI3K pathway and TNFa production, making it useful for various inflammatory diseases research [1] [2].

• Smiles :

  [H][C@]12Cc3c(c(C)cc(O)c3O)[C@]1(C)CC[C@@]1([H])C(C)(C)CCC[C@]21C

• Molecular Formula :

  C22H32O2

• Molecular Weight :

  328.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  849669-54-1