AQX-016A

CAT: 0931-MF-0063084-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0063084-01Size:25 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
849669-54-1
Target
Others|||PI3K|||Phosphatase|||TNF
Related Pathways
PI3K/Akt/mTOR signaling|||Others|||Apoptosis|||Metabolism
Bioactivity
AQX-016A is an orally active and potent SHIP1 agonist. It is a structural analog of pelorol and is three times more potent than the marine natural product pelorol at the same molar concentration. AQX-016A can activate recombinant SHIP1 enzyme in vitro and stimulate SHIP1 activity. It also inhibits the PI3K pathway and TNFa production, making it useful for various inflammatory diseases research [1] [2].
Smiles
[H][C@]12Cc3c(c(C)cc(O)c3O)[C@]1(C)CC[C@@]1([H])C(C)(C)CCC[C@]21C
Molecular Formula
C22H32O2
Molecular Weight
328.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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