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AQX-435

CAT: 0931-T62724-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62724-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1619983-52-6
Target
Others, Apoptosis, Phosphatase
Related Pathways
Others, Metabolism, Apoptosis
Bioactivity
AQX-435 is a potent activator of SHIP1 (SH2 domain-containing inositol-5′-phosphatase 1) . AQX-435 decreases B-cell receptor (BCR) downstream PI3K activity, induces apoptosis in malignant B cells, and exhibits inhibitory effects on lymphoma growth.
Smiles
C(=O)([C@@H]1[C@]2(C)[C@@](C[C@@H](NC(=O)C=3C=CC=NC3)[C@H]1C)(C(C)(C)CCC2)[H])C4=CC(O)=CC(O)=C4
Molecular Formula
C27H34N2O4
Molecular Weight
450.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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