PF-05186462

• Target :

  Sodium Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  0.9937

• Bioactivity :

  PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.

• Smiles :

  O(C1=C(C=C(C(F)(F)F)C=C1)C=2C=CN=NC2)C3=C(Cl)C=C(S(NC4=NN=CS4)(=O)=O)C(F)=C3

• Molecular Formula :

  C19H10ClF4N5O3S2

• Molecular Weight :

  531.89

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1235406-03-7