Masitinib mesylate

• Target:

  PDGFR|||c-Kit|||FAK|||Apoptosis|||FGFR|||Src

• Related Pathways:

  Apoptosis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity:

  >99.99%

• Bioactivity:

  Masitinib mesylate (AB-1010 mesylate) is a selective, orally bioavailable c-Kit inhibitor with an IC50 of 200 nM for human recombinant c-Kit, and IC50 values of 540/800 nM and 510 nM for PDGFR?/? and LynB, respectively.

• Smiles:

  CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1

• Molecular Formula:

  C29H34N6O4S2

• Molecular Weight:

  594.75

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1048007-93-7