Capmatinib xHCl

• Target:

  Apoptosis|||c-Met/HGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Apoptosis

• Purity:

  0.9981

• Bioactivity:

  Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM) .

• Smiles:

  Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

• Molecular Formula:

  C23H18ClFN6O

• Molecular Weight:

  448.89

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1029714-89-3