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LC3-mHTT-IN-AN1

CAT: 0931-T8081-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T8081-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
486443-73-6
Target
ATTECs, Autophagy, ATG
Related Pathways
PROTAC, Autophagy
Purity
0.9726
Bioactivity
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Smiles
Oc1cc(\C=C2/C(=O)Nc3ccc(Br)cc23)cc(Br)c1O
Molecular Formula
C15H9Br2NO3
Molecular Weight
411.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C