(S,R,S)-AHPC-Me-C7 ester

• UNSPSC Description:

  (S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/s-r-s-ahpc-me-c7-ester.html

• Purity:

  95.49

• Solubility:

  DMSO : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C([C@@H](NC(CCCCCC(OCC)=O)=O)C(C)(C)C)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](C1)O

• Molecular Weight:

  614.80

• References & Citations:

  [1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2639528-48-4