(S,R,S)-AHPC-Me-decanedioic acid

• UNSPSC Description:

  (S,R,S)-AHPC-Me-decanedioic acid is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/s-r-s-ahpc-me-decanedioic-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCCCCCCCC(N[C@H](C(N1C[C@@H](C[C@H]1C(N[C@@H](C)C2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C)=O)=O

• Molecular Weight:

  628.82

• References & Citations:

  [1]Pal P, et al. Discovery of a Novel BCL-XL PROTAC Degrader with Enhanced BCL-2 Inhibition. J Med Chem. 2021 Oct 14;64(19):14230-14246.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2380273-45-8