(S,R,S)-AHPC-C7-amine (dihydrochloride)

(S,R,S)-AHPC-C7-amine (dihydrochloride)

• CAS Number: 2415256-17-4
• UNSPSC Description: (S,R,S)-AHPC-C7-amine dihydrochloride is the dihydrochloride form of (S,R,S)-AHPC-C7-amine (HY-136186). (S,R,S)-AHPC-C7-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker. (S,R,S)-AHPC-C7-amine can be used for estrogen-related receptor α (ERRα) PROTAC degrader[1][2].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-c7-amine-dihydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: NCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O.Cl.Cl
• Molecular Weight: 644.70
• References & Citations: [1]Plewe MB, et al. Compounds and methods of treating diseases. WO2022068933A1. 2022-04-07.|[2]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported