HDAC8-IN-1

• Target :

  HDAC

• Related Pathways :

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity :

  0.9983

• Bioactivity :

  MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5) . HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

• Smiles :

  COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1

• Molecular Formula :

  C22H19NO3

• Molecular Weight :

  345.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1417997-93-3