HDAC8-IN-1

• Target:

  HDAC

• Related Pathways:

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity:

  0.9983

• Bioactivity:

  MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5) . HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

• Smiles:

  COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1

• Molecular Formula:

  C22H19NO3

• Molecular Weight:

  345.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1417997-93-3