GSK-J1

• Target:

  Histone Demethylase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9967

• Bioactivity:

  GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.

• Smiles:

  OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1

• Molecular Formula:

  C22H23N5O2

• Molecular Weight:

  389.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1373422-53-7