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GSK-J4

CAT: 0931-T3100-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T3100-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1373423-53-0
Target
Histone Demethylase, Apoptosis
Related Pathways
Chromatin/Epigenetic, Apoptosis
Purity
0.9998
Bioactivity
GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A (IC50=8.6/6.6 μM) . GSK-J4 induces endoplasmic reticulum stress-related apoptosis.
Smiles
CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
Molecular Formula
C24H27N5O2
Molecular Weight
417.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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TRC-G797555-100MGGSK J4
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