GSK-J4

• Target :

  Histone Demethylase|||Apoptosis

• Related Pathways :

  Chromatin/Epigenetic|||Apoptosis

• Purity :

  0.9998

• Bioactivity :

  GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A (IC50=8.6/6.6 ?M) . GSK-J4 induces endoplasmic reticulum stress-related apoptosis.

• Smiles :

  CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1

• Molecular Formula :

  C24H27N5O2

• Molecular Weight :

  417.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1373423-53-0