GSK-114

• Target :

  MAPK|||Others

• Related Pathways :

  Others|||MAPK

• Purity :

  0.9966

• Bioactivity :

  GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.

• Smiles :

  CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1

• Molecular Formula :

  C19H23N5O4S

• Molecular Weight :

  417.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1301761-96-5