GSK-114

• Target:

  MAPK|||Others

• Related Pathways:

  Others|||MAPK

• Purity:

  0.9966

• Bioactivity:

  GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.

• Smiles:

  CNS (=O) (=O) c1ccc (N (C) C) c (Nc2ncnc3cc (OC) c (OC) cc23) c1

• Molecular Formula:

  C19H23N5O4S

• Molecular Weight:

  417.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1301761-96-5