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GSK-114

CAT: 0931-T22341-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T22341-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1301761-96-5
Target
MAPK, Others
Related Pathways
Others, MAPK
Purity
0.9966
Bioactivity
GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.
Smiles
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1
Molecular Formula
C19H23N5O4S
Molecular Weight
417.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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