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HS-1371

CAT: 0931-T6815-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T6815-05Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2158197-70-5
Target
RIP kinase
Related Pathways
Apoptosis, NF-κB
Purity
0.98
Bioactivity
HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.
Smiles
Cc1ccc(Oc2ccnc3cc(ccc23)-c2cnn(c2)C2CCNCC2)cc1
Molecular Formula
C24H24N4O
Molecular Weight
384.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

7-(1-(Piperidin-4-yl)-1h-pyrazol-4-yl)-4-(p-tolyloxy)quinoline
CAS Number2158197-70-5
PubChem CID134817449
IUPAC Name4-(4-methylphenoxy)-7-(1-piperidin-4-ylpyrazol-4-yl)quinoline
Molecular FormulaC24H24N4O
Molecular Weight384.5
XLogP4
Topological Polar Surface Area52
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity517
SMILES
CC1=CC=C(C=C1)OC2=C3C=CC(=CC3=NC=C2)C4=CN(N=C4)C5CCNCC5
InChI
InChI=1S/C24H24N4O/c1-17-2-5-21(6-3-17)29-24-10-13-26-23-14-18(4-7-22(23)24)19-15-27-28(16-19)20-8-11-25-12-9-20/h2-7,10,13-16,20,25H,8-9,11-12H2,1H3
InChIKey
VPVLPCIBKVWFDT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-(1-(Piperidin-4-yl)-1h-pyrazol-4-yl)-4-(p-tolyloxy)quinoline
CAS: 2158197-70-5
CID: 134817449
Formula: C24H24N4O
MW: 384.5
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight384.5
XLogP34
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass384.19501140
Monoisotopic Mass384.19501140
Topological Polar Surface Area52 Ų
Heavy Atom Count29
Formal Charge0
Complexity517
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BA3498-100HS-1371
A18653-100HS-1371 100mg
A18653-50HS-1371 50mg
A18653-10HS-1371 10mg
A18653-5HS-1371 5mg
A18653-25HS-1371 25mg
A18653-1HS-1371 1mg
A18653-10mM-DHS-1371 10mM * 1mL in DMSO

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