BMS-911543

• Target:

  Tyrosine Kinases|||JAK|||Histone Methyltransferase

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||JAK/STAT signaling|||Angiogenesis|||Stem Cells

• Purity:

  0.9998

• Bioactivity:

  BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.

• Smiles:

  CCn1c (cc2c1nc (Nc1cc (C) n (C) n1) c1ncn (C) c21) C (=O) N (C1CC1) C1CC1

• Molecular Formula:

  C23H28N8O

• Molecular Weight:

  432.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1271022-90-2