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BMS-911543

CAT: 0931-T6790-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6790-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1271022-90-2
Target
Tyrosine Kinases, JAK, Histone Methyltransferase
Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis, Stem Cells
Purity
0.9998
Bioactivity
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
Smiles
CCn1c(cc2c1nc(Nc1cc(C)n(C)n1)c1ncn(C)c21)C(=O)N(C1CC1)C1CC1
Molecular Formula
C23H28N8O
Molecular Weight
432.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C