Nutlin-3b

• Target:

  E1/E2/E3 Enzyme|||Mdm2|||MDM-2/p53

• Related Pathways:

  Ubiquitination|||Apoptosis

• Purity:

  0.9883

• Bioactivity:

  Nutlin-3b ((+) -Nutlin-3) is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 ?M), 150-fold less potent (+) -enantiomer of Nutlin-3 as in comparison with opposite (-) -enantiomer Nutlin-3a.

• Smiles:

  COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1

• Molecular Formula:

  C30H30Cl2N4O4

• Molecular Weight:

  581.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  675576-97-3