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Pacritinib hydrochloride

CAT: 0931-T64283-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64283-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1228923-43-0
Target
Others, JAK
Related Pathways
Others, JAK/STAT signaling, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Stem Cells
Bioactivity
Pacritinib hydrochloride is a potent inhibitor of wild-type JAK2 (IC50: 23 nM) and the JAK2V617F mutant (IC50: 19 nM), and can be used in the study of acute myeloid leukaemia (AML) and myelofibrosis (MF) .
Molecular Formula
C28H32N4O3.xClH
Shipping Conditions
Ice Packs
Storage Temperature
-20°C