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HDAC1/6-IN-1

CAT: 0931-T64187-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64187-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2630989-02-3
Target
Others, Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair, Others
Bioactivity
HDAC1/6-IN-1 is a potent multi-target inhibitor of GLP (IC50: 1.3 nM), HDAC6 (IC50: 13 nM) and HDAC1 (IC50: 89 nM) . HDAC1/6-IN-1 inhibits the methylation and deacetylation of H3K9 at the protein level. HDAC1/6-IN-1 can block the cell cycle of cancer cells in G0/G1 phase, induce apoptosis and prevent cancer cell migration and invasion.
Smiles
N(C=1C2=C(N=C(N1)N3CCN(CCCCCC(NO)=O)CC3)C=C(OC)C(OC)=C2)C4CCN(CC5=CC=CC=C5)CC4
Molecular Formula
C32H45N7O4
Molecular Weight
591.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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