Edoxaban hydrochloride

• Target:

  Others|||Thrombin|||Factor Xa

• Related Pathways:

  Proteases/Proteasome|||Others|||Metabolism

• Bioactivity:

  Edoxaban (DU-176b) hydrochloride is a potent, selective, orally active, direct inhibitor of Factor Xa (FXa), targeting human free FXa (Ki: 0.561 nM) and thrombinogenase (Ki: 2.98 nM) . Over 10,000 times more selective than other thrombinases, it is suitable for studies to prevent thromboembolic disease.

• Smiles:

  Cl.CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1

• Molecular Formula:

  C24H31Cl2N7O4S

• Molecular Weight:

  584.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  480448-29-1