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Edoxaban hydrochloride

CAT: 0931-T64126-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64126-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
480448-29-1
Target
Others, Thrombin, Factor Xa
Related Pathways
Proteases/Proteasome, Others, Metabolism
Bioactivity
Edoxaban (DU-176b) hydrochloride is a potent, selective, orally active, direct inhibitor of Factor Xa (FXa), targeting human free FXa (Ki: 0.561 nM) and thrombinogenase (Ki: 2.98 nM) . Over 10,000 times more selective than other thrombinases, it is suitable for studies to prevent thromboembolic disease.
Smiles
Cl.CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1
Molecular Formula
C24H31Cl2N7O4S
Molecular Weight
584.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C