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Edoxaban (hydrochloride)

CAT: 0804-HY-10264CSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-10264CSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Edoxaban (DU-176b) hydrochloride is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban hydrochloride exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban hydrochloride can be used for preventing thromboembolic disease research[1].
CAS Number
480448-29-1
Product Name Alternative
DU-176 (hydrochloride)
UNSPSC
12352005
Target
Factor Xa; Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/edoxaban-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)C)[C@@H](CC1)C[C@H]([C@H]1NC(C(NC(C=C2)=NC=C2Cl)=O)=O)NC(C3=NC(CC4)=C(CN4C)S3)=O.[H]Cl
Molecular Formula
C24H31Cl2N7O4S
Molecular Weight
584.52
References & Citations
[1]Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6 (9) :1542-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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