MAP855

• Target :

  ERK|||MEK|||Others

• Related Pathways :

  Others|||MAPK

• Bioactivity :

  MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutant MEK1/2.

• Smiles :

  [H][C@@]1(CCN(C[C@@H]1F)C(=O)CO)n1c(C)nc2cnc3cc(F)c(cc3c12)-c1ccc(Oc2ncccn2)cc1Cl

• Molecular Formula :

  C28H23ClF2N6O3

• Molecular Weight :

  564.97

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1660107-77-6