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MAP855

CAT: 0931-T64001-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T64001-01Size:10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1660107-77-6
Target
ERK|||MEK|||Others
Related Pathways
Others|||MAPK
Bioactivity
MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutant MEK1/2.
Smiles
[H][C@@]1(CCN(C[C@@H]1F)C(=O)CO)n1c(C)nc2cnc3cc(F)c(cc3c12)-c1ccc(Oc2ncccn2)cc1Cl
Molecular Formula
C28H23ClF2N6O3
Molecular Weight
564.97
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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