Products for Research Use Only
RegisterLogin

SHP2 inhibitor LY6

CAT: 0931-T63993-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T63993-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2296718-09-5
Target
Others, Phosphatase
Related Pathways
Metabolism, Others
Bioactivity
SHP2 inhibitor LY6 (LY6) is a potent and selective compound that inhibits SHP2 with an IC50 of 9.8 μM, effectively blocking SHP2-mediated cell signaling and proliferation.
Smiles
O=C1N(C=2C(N1)=CC=CC2)C=3CN(CC4=C(OCC)C=C(O)C(C(/C=C/C5=C(Cl)C=C(Cl)C=C5)=O)=C4)CCC3
Molecular Formula
C30H27Cl2N3O4
Molecular Weight
564.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

SHP2 inhibitor LY6
CAS Number2296718-09-5
PubChem CID137796282
IUPAC Name3-[1-[[5-[(E)-3-(2,4-dichlorophenyl)prop-2-enoyl]-2-ethoxy-4-hydroxyphenyl]methyl]-3,6-dihydro-2H-pyridin-5-yl]-1H-benzimidazol-2-one
Molecular FormulaC30H27Cl2N3O4
Molecular Weight564.5
XLogP6.1
Topological Polar Surface Area82.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Heavy Atom Count39
Formal Charge0
Complexity945
SMILES
CCOC1=CC(=C(C=C1CN2CCC=C(C2)N3C4=CC=CC=C4NC3=O)C(=O)/C=C/C5=C(C=C(C=C5)Cl)Cl)O
InChI
InChI=1S/C30H27Cl2N3O4/c1-2-39-29-16-28(37)23(27(36)12-10-19-9-11-21(31)15-24(19)32)14-20(29)17-34-13-5-6-22(18-34)35-26-8-4-3-7-25(26)33-30(35)38/h3-4,6-12,14-16,37H,2,5,13,17-18H2,1H3,(H,33,38)/b12-10+
InChIKey
KXGGLZVQMDYPEO-ZRDIBKRKSA-N
Chemical Structure
2D Structure
2D structure of SHP2 inhibitor LY6
CAS: 2296718-09-5
CID: 137796282
Formula: C30H27Cl2N3O4
MW: 564.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight564.5
XLogP36.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass563.1378617
Monoisotopic Mass563.1378617
Topological Polar Surface Area82.1 Ų
Heavy Atom Count39
Formal Charge0
Complexity945
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T202752-01SHP2 inhibitor CNBDA
T210874-01SHP2-IN-40
T209308-01SHP2-IN-26
T207602-01SHP2-IN-37
T40121SHP2-D26
T61891-01SHP2-IN-8
T81165-01SHP2-IN-17
T81161-01SHP2-IN-21
T212530-01SHP2-IN-42
T212248-01SHP2-IN-43

Alternative Products

CatalogName
HY-125257SHP2 inhibitor LY6
GTR19241781-01SHP2 inhibitor CNBDA
bs-60319C-01SHP099 xHCl --- SHP2 Phosphatase Inhibitor
E8ET1611-80SHP2
GTR18155704SHP2 Antibody
HY-172911-01SHP2-IN-37
HY-172454SHP2-IN-36
HY-171959SHP2-IN-39
HY-176796SHP2-IN-43
HY-145162-01SHP2-D26

Popular Products