RET-IN-1

• Target:

  Others|||c-RET

• Related Pathways:

  Apoptosis|||Others|||Tyrosine Kinase/Adaptors

• Bioactivity:

  RET-IN-1 is a RET kinase inhibitor with IC50 values of 1 nM for RET (WT), 7 nM for RET (V804M), and 101 nM for RET (G810R) .

• Smiles:

  C (#N) C1=C2C (=CC (OC[C@H]3CNCCO3) =CN2N=C1) C=4C=NC (=CN4) N5CC6N (CC=7C=CC (OC) =NC7) C (C5) C6

• Molecular Formula:

  C29H31N9O3

• Molecular Weight:

  553.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2222755-14-6