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G12Si-1

CAT: 0931-T63758-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63758-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Ras
Related Pathways
MAPK, GPCR/G Protein, Others
Bioactivity
G12Si-1 is a selective, covalent K-Ras (G12S) inhibitor that inhibits K-Ras (G12S) oncogenic signaling. On mutant serine residues, G12Si-1 binds K-Ras (G12S) well.G12Si-1 may also be able to impede Sos-catalyzed exchange and inhibit EDTA-facilitated exchange rates, thereby affecting the nucleotide cycle of K-Ras.
Molecular Formula
C29H32ClN5O3
Molecular Weight
534.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-150926G12Si-1
HY-150927G12Si-2
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OF59775-011,1,1,1,1-Kestoheptaose
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