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HSP90-IN-11

CAT: 0931-T63528-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63528-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, HSP
Related Pathways
Others, Cytoskeletal Signaling, Metabolism
Bioactivity
HSP90-IN-11 is a potent inhibitor of HSP90 and induces significant accumulation of the sub-G1 population. HSP90-IN-11 has a potent HSP90α inhibitory effect comparable to that of AUY-922 (Luminespib) . In CRC and NSCLC cells, HSP90-IN-11 exhibited significant anti-proliferative activity in the double-digit nM range.HSP90-IN-11 was able to rapidly degrade client proteins EGFR and Akt in NSCLC cells.
Molecular Formula
C27H30FN3O6
Molecular Weight
511.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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