Products for Research Use Only
RegisterLogin

RAF-IN-1

CAT: 0931-T63365-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T63365-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2695505-82-7
Target
Raf, Others
Related Pathways
Others, MAPK
Bioactivity
RAF-IN-1 is a potent inhibitor of b/cRAF, acting on cRAF (IC50: 3.8 nM), bRAFwt (IC50: 36 nM), and bRAFV600E (IC50: 29.4 nM), and inhibiting A375 and H358 cell lines carrying the bRAFV600E mutation with a GI50 of 3.4 and 2.9 nM, respectively.
Smiles
O=C1NC2(OC=3C1=CC=C(C3)C4=CC(NC(=O)C=5C=C(C(F)(F)F)N=CC5)=CC=C4C)CCOCC2
Molecular Formula
C26H22F3N3O4
Molecular Weight
497.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T12685-01RAF mutant-IN-1
T72605-01C-RAF kinase-IN-1
T63386-01Pan-RAF kinase inhibitor 1
T204155-01Pan-Raf/RTK inhibitor 1
T212031-01RAF-IN-2
T60727-01B-Raf IN 8
T64116-01B-Raf IN 5
T4194-01Raf inhibitor 2
T78183-01B-Raf IN 15
T209344-01B-Raf IN 17

Alternative Products

CatalogName
C0039-01C-raf 1 (Raf, Raf-1) discontinued
R0495-09HRaf (Raf-1, c-Raf) discontinued
C0039-01-HRPC-raf 1 (Raf, Raf-1) (HRP) discontinued
C0039-01-FITCC-raf 1 (Raf, Raf-1) (FITC) discontinued
C0039-01-BiotinC-raf 1 (Raf, Raf-1) (Biotin) discontinued
C0039-01-PEC-raf 1 (Raf, Raf-1) (PE) discontinued
C0039-01-APCC-raf 1 (Raf, Raf-1) (APC) discontinued
C0039-01-APC-raf 1 (Raf, Raf-1) (AP) discontinued
R0495-09ARaf, phosphorylated (Ser259) (Raf-1, c-Raf)
MBS609994-01Raf, phosphorylated (Ser621) (Raf-1, c-Raf)

Popular Products