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Lp-PLA2-IN-5

CAT: 0931-T63345-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63345-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2738877-85-3
Target
Others, Phospholipase
Related Pathways
Others, Metabolism
Bioactivity
Lp-PLA2-IN-5 is a potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor and an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH), a phospholipase A2 involved in lipoprotein lipid or phospholipid hydrolysis. Lp-PLA2-IN-5 (Compound 35) may have potential applications in studying diseases linked to Lp-PLA2 activity, including Alzheimer's disease and atherosclerosis.
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O=C1N2C(N3C[C@@](C2)(OCC3)[H])=CC(OCC4=CC(F)=C(OC5=CC(C(F)(F)F)=CC=C5)C(F)=C4)=N1
Molecular Formula
C23H18F5N3O4
Molecular Weight
495.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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