Lp-PLA2-IN-5

• Target:

  Others|||Phospholipase

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  Lp-PLA2-IN-5 is a potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor and an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH), a phospholipase A2 involved in lipoprotein lipid or phospholipid hydrolysis. Lp-PLA2-IN-5 (Compound 35) may have potential applications in studying diseases linked to Lp-PLA2 activity, including Alzheimer's disease and atherosclerosis.

• Smiles:

  O=C1N2C(N3C[C@@](C2)(OCC3)[H])=CC(OCC4=CC(F)=C(OC5=CC(C(F)(F)F)=CC=C5)C(F)=C4)=N1

• Molecular Formula:

  C23H18F5N3O4

• Molecular Weight:

  495.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2738877-85-3