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EGFR-IN-38

CAT: 0931-T63283-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63283-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2711105-50-7
Target
Others, EGFR
Related Pathways
JAK/STAT signaling, Others, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
EGFR-IN-38 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-38 exhibits potential for research in EGFR mutation-related diseases.
Smiles
NC1=C2N(N=C(C2=NC=N1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4
Molecular Formula
C25H24ClN7O2
Molecular Weight
489.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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