EGFR-IN-36

CAT: 0931-T63265-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63265-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2711105-54-1

Target

Others, EGFR

Related Pathways

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Others, Angiogenesis

Bioactivity

EGFR-IN-36 is a potent inhibitor of EGFR, acting on EGFR (WT) (IC50: 19.09 nM), HER2 (WT) (IC50: 120.01 nM), and HER2 (A775_G776insYVMA) (IC50: 2.35 nM) . EGFR-IN-36 exhibits potential for studying wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.

Smiles

NC=1C2=C(C=C(N2N=CN1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4

Molecular Formula

C26H25ClN6O2

Molecular Weight

488.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-144053	EGFR-IN-36
OM637475-01	Phospho-EGFR (S695) [SN07-36] Antibody
ET1611-50	Phospho-EGFR (S695) Recombinant Rabbit Monoclonal Antibody [SN07-36]
sc-80543	EGFR (EGFR.1)
ant-042	EGFR

EGFR-IN-36

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