RET-IN-9

• Target:

  Others|||c-RET

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Apoptosis|||Others

• Bioactivity:

  RET-IN-9 is a potent inhibitor of RET, a single-channel transmembrane receptor tyrosine kinase involved in kidney and enteric nervous system development, as well as in maintaining homeostasis in the nervous, endocrine, hematopoietic, and male reproductive systems. RET-IN-9 is potentially useful in studying RET-related diseases, including non-small cell lung cancer and medullary thyroid cancer.

• Smiles:

  C (#N) C1=C2C (=CC (NCC) =CN2N=C1) C=3C=NC (=CN3) N4CC5N (CC=6C=CC (OC) =NC6) C (C4) C5

• Molecular Formula:

  C26H27N9O

• Molecular Weight:

  481.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2649418-11-9