CDK6/PIM1-IN-1

CAT: 0931-T63071-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T63071-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2677026-14-9

Target

Others, Apoptosis, Pim, CDK

Related Pathways

JAK/STAT signaling, Apoptosis, Chromatin/Epigenetic, Others, Cell Cycle/Checkpoint

Bioactivity

CDK6/PIM1-IN-1 is a balanced, potent dual inhibitor of CDK6 (IC50: 39 nM) and PIM1 (IC50: 88 nM), also showing inhibitory activity on CDK4 (IC50: 3.6 nM) . It significantly inhibits the proliferation of acute myeloid leukemia (AML) cells, arrests the cell cycle in G1 phase, induces cell apoptosis, and demonstrates anti-AML activity.

Smiles

N(CC)(CC)C1=NC2=C(C=CC(=C2)C3=NC(NC4=CC=C(C=N4)N5CCNCC5)=NC=C3F)N=C1

Molecular Formula

C25H28FN9

Molecular Weight

473.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T206369-01	CDK2/PIM1-IN-1
T12474-01	PIM1-IN-1
T201591-01	CDK6-IN-1
T10828-01	CK2/PIM1-IN-1
T5093-01	Pim1/AKK1-IN-1
T40047	CDK6/9-IN-1
TMAB-11457-01	Anti-PIM1+PIM3 Polyclonal Antibody
T211649-01	PIM1-IN-8
T63720-01	PIM1-IN-3
T61700-01	PIM1-IN-7

Alternative Products

Catalog	Name
HY-142696	CDK6/PIM1-IN-1
HY-142696A-01	CDK6/PIM1-IN-1 (hydrochloride)
GTR19263363-01	CDK6/PIM1-IN-1 hydrochloride
BA6399-1	PIM1-IN-1
GTR19240525-01	CDK6-IN-1
HY-173224	CDK2/PIM1-IN-1
HY-135816	CK2/PIM1-IN-1
HY-10371-01	Pim1/AKK1-IN-1
A19392-50	PIM1-IN-1 50mg
A19392-25	PIM1-IN-1 25mg

CDK6/PIM1-IN-1

Related Products

Alternative Products

Popular Products