TM-1

• Target :

  Others|||Dehydrogenase

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 ?M) and PDHK2 (IC50: 5.2 ?M) . TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation.

• Smiles :

  COc1ccc(cc1OC)-c1c(C)c2ccc(OCCN3CCN(CCO)CC3)cc2oc1=O

• Molecular Formula :

  C26H32N2O6

• Molecular Weight :

  468.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  921099-13-0