Products for Research Use Only

TM-1

CAT: 0013-GTR19185554-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185554-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TM-1 is a cell-permeable PDHK inhibitor with IC50 values of 2.97 μM and 5.2 μM against PDHK1 and PDHK2, respectively. It activates the pyruvate dehydrogenase complex by blocking its phosphorylation and has been shown to suppress cancer cell proliferation in vitro, making it a useful tool for studying cancer metabolism.
CAS Number
921099-13-0
Field of Research
Cell Biology, Metabolism Research, Protein Biochemistry
Purity
99.61% (May vary between batches)
Smiles
O=C1OC2=CC (OCCN3CCN (CCO) CC3) =CC=C2C (=C1C=4C=CC (OC) =C (OC) C4) C
Molecular Formula
C26H32N2O6
Molecular Weight
468.54
Storage Conditions
-20°C
Notes
For research use only.

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