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AMG 837 hemicalcium

CAT: 0931-T62848Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T62848Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1291087-14-3
Target
Others, GPCR
Related Pathways
Endocrinology/Hormones, GPCR/G Protein, Others
Bioactivity
AMG 837 hemicalcium is a potent, orally active GPR40/FFA1 partial agonist that inhibits the specific binding of [3H]AMG 837 to the human FFA1 receptor (pIC50: 8.13) . It promotes insulin secretion and reduces glucose levels in rodents.
Smiles
CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.[Ca+2]
Molecular Formula
C52H40CaF6O6
Molecular Weight
914.954
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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